| 冬虫夏草固体发酵物水提液抗疲劳作用初步研究 |
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| 引用本文： | 闫文娟,李泰辉,劳景辉,沈亚恒,方佳茂. 冬虫夏草固体发酵物水提液抗疲劳作用初步研究[J]. 食用菌学报, 2012, 19(1): 61-64 |
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| 作者姓名： | 闫文娟 李泰辉 劳景辉 沈亚恒 方佳茂 |
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| 作者单位： | 1. 广东省微生物研究所,广东省菌种保藏与应用重点实验室,广东省微生物应用新技术公共实验室,广东省华南应用微生物重点实验室—省部共建国家重点实验室培育基地,广东广州510070
2. 广东环西生物科技股份有限公司,广东普宁,515343 |
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| 基金项目： | 广东省基金，广东省科技计划项目，广东省产学研项目 |
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| 摘 要： | 通过研究冬虫夏草(Ophiocordyceps sinensis)固体发酵物水提液对负重小鼠游泳时间的影响,初步探讨其抗疲劳作用。结果表明:与阴性对照组相比,灌胃喂养冬虫夏草固体发酵物水提液的小鼠负重游泳时间显著延长,证明在本试验条件下冬虫夏草固体发酵物具有显著的抗疲劳作用。
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| 关 键 词： | 冬虫夏草 小鼠 抗疲劳 |
Anti-fatigue Activity of Hot Aqueous Extracts of Ophiocordyceps sinensis Mycelium Evaluated Using a Mouse Model |
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| YAN Wenjuan , LI Taihui , LAO Jinghui , SHEN Yaheng , FANG Jiamao. Anti-fatigue Activity of Hot Aqueous Extracts of Ophiocordyceps sinensis Mycelium Evaluated Using a Mouse Model[J]. Acta Edulis Fungi, 2012, 19(1): 61-64 |
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| Authors: | YAN Wenjuan LI Taihui LAO Jinghui SHEN Yaheng FANG Jiamao |
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| Affiliation: | 1Guangdong Institute of Microbiology,Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangdong Open Laboratory of Applied Microbiology,State Key Laboratory of Applied Microbiology (Ministry-Guangdong Province Jointly Breeding Base),South China,Guangzhou,Guangdong 510070,China;2Huanxi Biological Technology Co.,Ltd,Puning,Guangdong 515343,China) |
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| Abstract: | Ophiocordyceps sinensis mycelium was grown in 250 mL glass bottles on a solid medium consisting of 1% glucose,0.5% peptone,0.3% yeast extract and 0.3% malt extract in distilled water mixed with rice(1.5∶1).Hot(80-99 ℃) aqueous extracts of fungal mycelium grown for 25-30 d were administered to mice as part of their daily liquid intake(0.2 mL/10 g body weight) for 30 d and the anti-fatigue effects were evaluated using the weight-loaded swimming times of the mice as indicator.Extracts at a dose level of 1.27 g/kg·body weight had a significant(P<0.05) anti-fatigue effect compared with untreated controls. |
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| Keywords: | Ophiocordyceps sinensis hot aqueous extracts anti-fatigue effects in mice |
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