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类脂作为佐剂对新城疫灭活疫苗免疫效果的影响
引用本文:张兴晓,刘美丽,杨灵芝,王秀云,韩新会.类脂作为佐剂对新城疫灭活疫苗免疫效果的影响[J].中国家禽,2007,29(17):11-13.
作者姓名:张兴晓  刘美丽  杨灵芝  王秀云  韩新会
作者单位:1. 山东博莱威生物技术研究所,山东滨州,256606;山东农业大学动物科技学院,山东泰安,271018
2. 山东博莱威生物技术研究所,山东滨州,256606
摘    要:对免疫新城疫(ND)类脂灭活疫苗的雏鸡分别于免疫后2、7、14、21、28、35和42 d进行法氏囊、脾脏、胸腺指数测定,以注射生理盐水、ND抗原、类脂的鸡只为对照.结果表明,免疫后2~14 d,各组指数差异不显著,14 d以后,疫苗组与其他组比较差异显著,与类脂组差异不显著.表明,类脂作为佐剂用于制备ND疫苗,具有较强的免疫增强作用.

关 键 词:新城疫  类脂灭活疫苗  免疫增强
修稿时间:2007年4月29日

Effects of Poplar Bark Lipid as Adjuvants on Immune Effects of Inactivated Vaccine against Newcastle Disease Virus
Zhang Xingxiao,Liu Meili,Yang Lingzhi,Wang Xiuyun,Han Xinhui.Effects of Poplar Bark Lipid as Adjuvants on Immune Effects of Inactivated Vaccine against Newcastle Disease Virus[J].China Poultry,2007,29(17):11-13.
Authors:Zhang Xingxiao  Liu Meili  Yang Lingzhi  Wang Xiuyun  Han Xinhui
Abstract:The chickens inoculated with poplar bark lipid inactivated vaccine against Newcastle disease (ND) was detected on bursa,spleen and thymus index at 2,7,14,21,28,35,42 day after inoculation,respectively. The chickens were injected physiological salt solution,ND antigen,poplar bark lipid as control groups. The results showed that the indexes had no significant difference at 2 to 14 day after inoculation. But 14 days later, the difference was significant between vaccine group and control groups. The poplar bark lipid had clear strong immunopotentiation function.
Keywords:ND  poplar bark lipid inactivated vaccine  immunopotentiation
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