Pre-purchase testing for drugs in horses: A review |
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| Authors: | Thomas Tobin MRCVS PhD Jerry W Blake PhD |
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| Institution: | 1. Center for Surgery and Public Health, Division of Urological Surgery, Brigham and Women''s Hospital, Harvard Medical School, Boston, Massachusetts;2. Research Program in Men''s Health: Aging and Metabolism, Brigham and Women''s Hospital, Harvard Medical School, Boston, Massachusetts;3. Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women''s Hospital, Boston, Massachusetts;4. Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts;5. Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts;6. Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;7. Department of Urology, Marien Hospital Herne, Ruhr-University Bochum, Herne, Germany;8. Department of Urology, University Hospital Frankfurt, Frankfurt, Germany;1. Physiology and Human Performance Research Group, Department of Physiology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil;2. “Paes de Carvalho” Laboratory of Biophysics of Heart, Department of Physiology, Federal University of Sergipe, Aracaju, Brazil;3. Department of Sport Sciences, Federal University of Triângulo Mineiro, Uberaba, Brazil;1. Laboratory of Equine Exercise Physiology and Pharmacology, Department of Animal Morphology and Physiology, Faculdade de Ciências Agrárias e Veterinárias, UNESP—Univ Estadual Paulista, Jaboticabal, São Paulo, Brazil;2. Department of Animal Breeding and Nutrition, Faculdade de Medicina Veterinária e Zootecnia, UNESP—Univ Estadual Paulista, Botucatu, São Paulo, Brazil;3. Hospital Veterinário, Faculdade de Agronomia e Medicina Veterinária, Campus Universitário Darcy Ribeiro, Asa Norte, UnB—Universidade de Brasília, Brasília, Distrito Federal, Brazil;1. Institute of Sciences of Food Production, National Research Council (CNR), Via G. Amendola 122/O, 70126, Bari, Italy;2. Department of Agricultural and Environmental Science, University of Bari ‘Aldo Moro’, Via Amendola 165/A, I-70126, Bari, Italy;1. Department of Emergency Medicine, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands;2. Regional Ambulance Service Hollands Midden (RAVHM), vondellaan 43, 2332 AA Leiden, The Netherlands |
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| Abstract: | The use of medications to mask defects of wind, limb or temperament in horses offered for sale can be a problem for purchasers, and for veterinarians performing pre-purchase examinations. Drugs which may be used in this way include the phenylbutazone-like drugs, cotricosteroids, local anaesthetics, and tranquilizers. If skillfully used, no signssuggestive of medication by these agents will be detectable by the examining veterinarian. In the absence of information on the medications status of an animal, the usefulness of a pre-purchase examination may be limited.These limitations can be circumvented by the analysis of blood or more expecially blood and urine samples from such horses. Current analytical methodology allows the detection of many medications in blood, and of virtually all significant medications if blood and urine samples are available. Such analysis, therefore, allows the veterinary practitioner to offer a significantly better pre-purchase test, and protects both the veterinarian and the purchaser. |
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