缓释复合酸化剂对断奶仔猪消化道酸度及肠道功能的影响

本试验选用28 R龄断奶、平均体质量(7.00±0.10)kg的长白猪(♂)×大白猪(♂)二元杂交仔猪64头,按单因索试验设计原则,研究在玉米一豆粕一膨化大豆型基础日粮中添加不同类型(包被未包被)复合酸化剂对断奶仔猪胃肠道酸度、生产性能、肠组织形态、消化酶活性、肠道微生物菌群及肠黏膜抗体SIgA的影响.试验设4个处理,每个处理4个重复,每个重复4头猪(公母各半),饲养试验时间为35 d.结果表明,微胶囊型缓释复合酸化剂可以极显著降低断奶仔猪胃和小肠pH(P＜0.01);极显著提高空肠绒毛高度和隐窝深度的比值(P＜0.01);断奶前期,显著提高小肠蔗糖酶和乳糖酶活性(P＜0.05);断奶后期,极显著提高仔猪盲肠和结肠中乳酸杆菌数量,降低大肠杆菌数量(P＜0.01);微胶囊型缓释复合酸化剂还有增加仔猪肠黏膜抗体SIgA分泌量的趋势(P＞0.05).结果提示,在断奶仔猪日粮中添加微胶囊型缓释复合酸化剂,可以通过降低肠道pH,优化肠道微生物区系,改善肠组织形态和功能,从而提高断奶仔猪肠道的消化力和适应性,并促进仔猪生长.

Effects of Slow-release Compound Acidifiers on Gastrointestinal PH and Intestinal Function in Weaning Piglets

.The experiment was conducted to study the effects of the addition of encapsulated and non-encapsulated compound acidifiers in a diet based on corn-soybean meal-extruded soybean on gastrointestinal pH, growth performance, villus height and crypt depth of jejunum, intestinal digestive enzymes activities, microbial population and intestinal mucosal secretory immunoglobulin A (SIgA) in weaning piglets. Sixty-four 28-day-old, crossbred piglets (Landrace × Large White), weighing an average of (7.00±0. 10) kg, were randomly assigned into four treatments with four replicates and four piglets (2 male and 2 female) per pen, according to single-factor design principle. The feeding trial lasted for 35 days. The results showed that microcapsule slowrelease compound acidifiers significantly reduced the pH in stomach and small intestine(P＜0.01). In addition, microcapsule slow-release compound acidifiers significantly increased the ratio of the villus height to crypt depth of jejunum(P＜0.01), and stimulated the sucrase activity and lactase activity in the early weaning period(P＜0.05)as well. During the later weaning period,microcapsule compound acidifiers significantly increased the counts of lactobacillus and decreased the counts of Escherichia coli in the cecum and the colon(P＜0.01). It was also noted that there was an tendency of lower secretion of intestinal mucosal secretory IgA(P＞0.05). These results indicated that the microcapsule slow-release compound acidifiers could optimize the intestinal microflora and improve the intestinal morphology and function by reducing the gastrointestinal pH,so as to enhance the intestinal digestibility and adaptation, and consequently improve the growth performance in weaning piglets.