紫苏籽活性成分的抗炎作用及其在畜牧生产中的应用研究进展

紫苏籽是一味药食两用的传统中药材,具有解热镇痛,抑菌消炎等功效。紫苏籽富含α-亚麻酸,而α-亚麻酸有助于维持免疫细胞正常的结构与功能,并能抑制炎症因子的产生;紫苏醛既能抑制促炎因子基因的表达,又可提升动物自身的免疫能力;黄酮及酚酸类等活性物质能减少炎症细胞浸润和水肿形成,诱导病变细胞凋亡,还具有抗氧化等作用。文章主要介绍了紫苏籽中α-亚麻酸、紫苏醛、异紫苏酮、木犀草素和迷迭香酸等主要抗炎活性成分及抗炎作用,综述了紫苏籽在畜牧生产中的研究进展,介绍了紫苏籽在动物肠道菌群、生产性能、免疫功能、肉品质等方面的调节作用。此外,还探讨了不同品种紫苏籽间成分含量差异大、部分品种的毒副作用强等问题,旨在为紫苏籽资源的开发利用提供理论参考。

Research Progress on Anti-inflammatory Effects of Active Components of Perilla Seeds and Their Application in Livestock Production

Perilla seed is a traditional Chinese medicine with antipyretic,analgesic and anti-inflammatory effects.It is rich with α-linolenic acid which is involved in maintaining the normal structure and function of immune cells and inhibiting the production of inflammatory factors.Perillaldehyde can inhibit the expression of pro-inflammatory factor genes and enhance immunity capability of animals.Flavonoids,phenolic acids and other active substances can reduce infiltration of inflammatory cell and the formation of edema,induce apoptosis of diseased cells,and also have antioxidant effects.This paper mainly introduces the main anti-inflammatory active ingredients and anti-inflammatory effects of α-linolenic acid,perillaldehyde,iso-perillaldehyde,luteolin and rosmarinic acid in Perilla seed.The research progress of its application in livestock production was reviewed,and the regulation of Perilla seed in animal intestinal flora,production performance,immune function and meat quality was analyzed.In addition,the problems of differences of ingredients contents with different varieties breeds and the strong adverse effects were also discussed,aiming to provide a theoretical reference for the development and utilization of Perilla seed.