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天津地区奶牛乳腺炎金葡菌黏附素Fnbp A基因检测
引用本文:孙英峰,杨宏军,池晶晶,王东,徐璇. 天津地区奶牛乳腺炎金葡菌黏附素Fnbp A基因检测[J]. 天津农业科学, 2011, 17(5): 48-49,52. DOI: 10.3969/j.issn.1006-6500.2011.05.013
作者姓名:孙英峰  杨宏军  池晶晶  王东  徐璇
作者单位:1. 天津市畜牧兽医研究所,天津,300112
2. 山东省农业科学院奶牛研究中心,山东济南,250100
基金项目:天津市农科院院长基金项目(08012); 天津市科技支撑计划重点项目(09ZCGYNC00100)
摘    要:金黄色葡萄球菌黏附素FnbpA是引起奶牛乳腺炎的关键因素之一,对金黄色葡萄球菌的黏附环节进行阻断,进而减少或阻止金葡菌相关毒素和荚膜的表达,以黏附素蛋白为靶抗原的亚单位疫苗是预防奶牛金葡菌乳房炎的发展方向之一。对天津及周边地区奶牛乳腺炎金黄色葡萄球菌临床分离株的黏附素FnbpA基因检测研究,结果表明96%的临床分离株携带此基因,为进一步研究天津地区奶牛乳房炎金葡菌亚单位疫苗提供理论依据。

关 键 词:奶牛乳腺炎  金黄色葡萄球菌  Fnbp A  检测

Detection of Staphylococcus aureus Adhesin Fnbp A of Cow Mastitis in Tianjin
SUN Ying-feng,YANG Hong-jun,CHI Jing-jing,WANG Dong,XU Xuan. Detection of Staphylococcus aureus Adhesin Fnbp A of Cow Mastitis in Tianjin[J]. Tianjin Agricultural Sciences, 2011, 17(5): 48-49,52. DOI: 10.3969/j.issn.1006-6500.2011.05.013
Authors:SUN Ying-feng  YANG Hong-jun  CHI Jing-jing  WANG Dong  XU Xuan
Affiliation:SUN Ying-feng1,YANG Hong-jun2,CHI Jing-jing1,WANG Dong1,XU Xuan1(1. Tianjin Institute of Animal Husbandry and Veternary Medicine,Tianjin 300112,China,2. Dairy Research Center,Shandong Academy of Agricultural Sciences,Jinan,Shandong 250100,China)
Abstract:Staphylococcus aureus adhesin Fnbp A was one of the key factors that caused cow mastitis. If we intervene S.aureus adhesion ,and then it could reduce or prevent expression of toxin and capsule, and the adhesin as a target for vaccine development may be effective way to prevent the cow S.aureus mastitis. This study is doing research of Tianjin and surrounding areas cow mastitis clinical isolates of S.aureus adhesin Fnbp A of genetic, the results show 96% isolates stains carrying this gene. This test provids ...
Keywords:cow mastitis  S.aureus  Fnbp A  detection  
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