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猪消化道对不同工艺替米考星预混剂的吸收利用评价试验
引用本文:Keanpen,刘继根,赵易艺,温华鑫,罗昌. 猪消化道对不同工艺替米考星预混剂的吸收利用评价试验[J]. 中国猪业, 2021, 16(6): 63-66. DOI: 10.16174/j.issn.1673-4645.2021.06.014
作者姓名:Keanpen  刘继根  赵易艺  温华鑫  罗昌
作者单位:1道勤生物科学(美国); 2长沙道勤生物科技有限公司,湖南长沙 410125
摘    要:为评价猪消化道对4种不同工艺替米考星预混剂的吸收利用率,试验对20头体重40 kg左右健康三元商品猪服药后的采食情况以及血药浓度结果进行分析.结果表明,"星月技术"包被的替米考星在猪体内起到了药物的缓释作用,减轻了药物对猪胃的刺激和胃酸对药效的影响,并且血中药物浓度高且药效持续时间更久.

关 键 词:替米考星    适口性  药代动力学  血药浓度
收稿时间:2021-10-12

Evaluation Test of Digestive Tract Absorption and Utilization of Swines with Tilmicosin Premix of Different Processes
Keanpen,LIU Jigen,ZHAO Yiyi,WEN Huaxin,LUO Chang. Evaluation Test of Digestive Tract Absorption and Utilization of Swines with Tilmicosin Premix of Different Processes[J]. China Swine Industry, 2021, 16(6): 63-66. DOI: 10.16174/j.issn.1673-4645.2021.06.014
Authors:Keanpen  LIU Jigen  ZHAO Yiyi  WEN Huaxin  LUO Chang
Affiliation:1Dogain Biosciences, America; 2Changsha Dogain Biosciences Co., Ltd, Changsha 410125, China
Abstract:In order to evaluated the effects of four different premixes of Tilmicosin on the absorption and utilization rate of swines' digestive tract, the analysis was conducted on the feed intake and plasma concentration results of 20 healthy ternary grocery pigs weighing about 40 kg. The results showed that, compared with the other three premix products of Tilmicosin technology, the "Xingyue technology" tilmicosin product did not affect the feed intake, and played a slow-release effect of the drug in the swine body, which reduced the drug's effect. Stomach irritation and gastric acid affected the efficacy of the drug, and the concentration of the drug in the blood was high and the efficacy lasts longer.
Keywords:Tilmicosin  swine  palatability  pharmacokinetics  plasma concentration  
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