Safety of vaccination against brucellosis with the rough strain in pregnant cattle |
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Authors: | Barbosa Adriana Agostini Figueiredo Ana Cristina Silva Palhao Miller Pereira Viana Joao Henrique Moreira Fernandes Carlos Antonio Carvalho |
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Affiliation: | 1.Universidade José do Rosário Vellano, Rodovia MG 179, Km 0, Campus Universitário, Alfenas, MG, 37130-000, Brazil ;2.Biotran Biotecnologia e Treinamento em Reprodu??o Animal, Rua Tatuin 447, Alfenas, MG, 37130-000, Brazil ;3.Embrapa Recursos Genéticos e Biotecnologia, PqEB, Av. W5N, Brasília, DF, 70770-917, Brazil ; |
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Abstract: | Brucellosis is an infectious and contagious disease that profoundly impacts public health. However, in many countries, disease prevention is restricted to the vaccination of calves, and there is no prophylactic strategy for pregnant heifers and cows. The aim of this study was to evaluate the safety of the rough strain vaccine against brucellosis in pregnant cattle. Crossbred cows (N = 96) at three gestational periods (early, mid, or late pregnancy) were randomly allocated into the vaccine treatment group or to the control group. We then compared the percentage of pregnancies reaching full term, live calves 60 days after delivery, and seropositive calves. There was no effect of vaccination in any of the gestational periods on the evaluation endpoints. In conclusion, vaccination against brucellosis with the rough strain is safe for pregnant cattle at all gestational periods. |
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