| 霞水母胶原蛋白活性肽对小鼠免疫功能的影响 |
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| 引用本文： | 邓超,汤鲁宏,陈伟,王琪,林丹.霞水母胶原蛋白活性肽对小鼠免疫功能的影响[J].安徽农业科学,2009,37(8):3557-3558. |
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| 作者姓名： | 邓超 汤鲁宏 陈伟 王琪 林丹 |
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| 作者单位： | 江南大学医药学院,江苏无锡,214122 |
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| 基金项目： | 国家农业科技成果转化资金项目(2007GB2C100105) |
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| 摘 要： | 目的]为霞水母胶原蛋白活性肽的临床应用提供理论依据。方法]在探明霞水母胶原蛋白肽急性毒性反应的基础上，分别以25、50、100mg／kg的剂量给小鼠连续灌胃30d，然后进行小鼠吞噬细胞吞噬功能、迟发型超敏反应、血清溶血素的测定。结果]霞水母胶原蛋白肽为实际无毒性或低毒性物质；试验组的3项免疫指标与空白对照组相比有显著（P〈0．05）或极显著（P〈0．01）差异。结论]霞水母胶原蛋白活性肽具有一定的免疫增强作用。
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| 关 键 词： | 霞水母 胶原蛋白活性肽 免疫增强 |
Effects of Collagen Peptide from Cyanea nozakii on Mice Immune Function |
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| DENG Chao et al.Effects of Collagen Peptide from Cyanea nozakii on Mice Immune Function[J].Journal of Anhui Agricultural Sciences,2009,37(8):3557-3558. |
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| Authors: | DENG Chao |
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| Institution: | DENG Chao et al(School of Medicine , Pharmaceutics,Jiangnan University,Wuxi,Jiangsu 214122) |
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| Abstract: | Objective] The study aimed to provide a theoretical basis for the clinical application of collagen peptide from Cyanea nozakii.Method] After acute toxicity test on mice,collagen peptide from C.nozakii were given to mice by continuous intragastric administration for 30 d at the doses of 25,50,100 mg/kg,and then the phagocytosis of macrophage,delayed type hypersensitivity(DTH) and serum hemolysin level were determined.Result] Collagen peptide from C.nozakii was atoxic or low toxic,and the three immune indi... |
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| Keywords: | Cyanea nozakii Collagen peptide Immunopotentiation |
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