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炎咳停口服液对大白鼠的亚急性毒性试验
引用本文:林雁春,马红霞,张燕京,关天颖,赵国良. 炎咳停口服液对大白鼠的亚急性毒性试验[J]. 吉林农业大学学报, 2003, 25(6): 669-671
作者姓名:林雁春  马红霞  张燕京  关天颖  赵国良
作者单位:1. 吉林农业大学动物科技学院,吉林,长春,130118
2. 吉林农业大学管理学院,吉林,长春,130118
3. 长春市双阳区农牧局,吉林,长春,130600
基金项目:吉林省牧业管理局资助项目(200127)
摘    要:利用大白鼠为试验模型,对炎咳停口服液进行了亚急性毒性试验,观察其对大白鼠的行为、饮食欲状况、体重变化、生理生化指标的影响,对组织器官和组织学变化及对实验动物的安全性等的影响。试验结果表明:炎咳停口服液临床应用剂量为0.5g/kg,对大白鼠的生理活动、生理生化指标、主要组织器官无不良影响,大白鼠未呈现毒性,应用安全。

关 键 词:炎咳停口服液 大白鼠 亚急性毒性试验 剂量 生理指标 生化指标 中药复方制剂
文章编号:1000-5684(2003)06-0669-03
修稿时间:2003-07-22

Subchronic Toxicity Studies of Yan-Ke-Ting Oral Liquid in Rats
LIN Yan-chun,MA Hong-xia,ZHANG Yan-jing,GUAN Tian-ying,ZHAO Guo-liang. Subchronic Toxicity Studies of Yan-Ke-Ting Oral Liquid in Rats[J]. Journal of Jilin Agricultural University, 2003, 25(6): 669-671
Authors:LIN Yan-chun  MA Hong-xia  ZHANG Yan-jing  GUAN Tian-ying  ZHAO Guo-liang
Affiliation:LIN Yan-chun~1,MA Hong-xia~1,ZHANG Yan-jing~2,GUAN Tian-ying~1,ZHAO Guo-liang~3
Abstract:Yan-Ke-Ting oral liquid was used in rats to test its effects on rats' behavior, appetite and body weight. Physiological and biochemical index, and organ and histology, were observed. Safety, possible toxicity and bad effects were also evaluated. The results showed that there was not any bad effect on rats when proper dosage of the liquid was used, including physiological activities, physiological and biological index, and main tissues and organ. No toxicity was observed.
Keywords:subchronic toxicity  physiological and biological traits  Yan-Ke-Ting oral liquid  rat
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