Biological functions and clinical significance of secretogranin III |
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| Authors: | LI Feng-rui TIAN Xiao-fei ZHOU Yi-shu ZHU Lan-hui PANG Hao |
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| Institution: | 1. School of Forensic Medicine, China Medical University, Shenyang 110001, China;
2. Department of Forensic Medicine, Baotou Medical College, Baotou 014060, China. |
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| Abstract: | AIM: Secretogranin III (SCG3/Sg III) is extensively distributed in endocrine or endocrine-like cells in human body and plays an important role in some biological functions by regulating peptide hormone secretion and neuroendocrine activity.The distribution and functions of SCG3 make itself as not only one of the most useful biological markers in association with neuroendocrine functions, but also a potential indicator of diagnostic and prognostic evaluation in certain diseases.The gene and protein structures, tissue expression, biological functions as well as pathophysiology and clinical significance of SCG3 are reviewed in this article. |
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| Keywords: | Secretogranin III Biological function |
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