| Abstract: | It is believed that the different classes of compound which interfere with photosynthesis system II (PS 11) must act by binding at different sites, because they appear to be structurally so dissimilar. However, it can be argued that some of the classes of compound of diverse structural type share very similar external surface features. Now that details about the binding oj PSII inhibitors are becoming available, it will be possible to see how many of the different compound classes actually bind similarly. In future, increasingly detailed knowledge of the structures of potential sites of action will be available. QSAR methods will need to be used together with molecular modelling to be effective tools for agrochemical design. |
