| 胰岛素样生长因子-1对动物被毛生长影响的研究进展 |
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| 引用本文： | 申艳,张丹瑾,王婷,谢建山,张昱,于秀菊,曹靖,赫晓燕.胰岛素样生长因子-1对动物被毛生长影响的研究进展[J].中国畜牧兽医,2013,40(10):169-172. |
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| 作者姓名： | 申艳 张丹瑾 王婷 谢建山 张昱 于秀菊 曹靖 赫晓燕 |
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| 作者单位： | 1. 山西农业大学动物科技学院, 山西太谷 030801;2. 北京农业职业学院, 北京 102442 |
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| 基金项目： | 国家自然科学基金项目(31172283);山西农业大学2009年引进人才科研启动项目(XB2009020);山西省重点学科建设经费:肉牛、肉羊标准化生产体系的建立—子项目—利用转microRNA技术培育彩色转基因细毛羊;山西省科技攻关项目(20080311034)。 |
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| 摘 要： | 动物被毛生长是一个复杂的过程,受遗传、内分泌、营养及外界条件等各种因素的影响。而胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)是一种具有促进细胞增殖、分化,调节物质代谢等多种生物活性的多肽分子。研究结果发现,IGF-1对被毛/毛发生长的影响不仅局限于自身,同时介导一些细胞因子对被毛生长的调节作用。为阐明IGF-1在被毛/毛发生长方面的重要作用,文章就国内外IGF-1对动物被毛生长影响的研究进展进行综述。
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| 关 键 词： | 动物 被毛/毛发生长 胰岛素样生长因子-1 信号通路 |
Research Progress on the Effect of IGF-1 on Hair Growth of Animals |
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| SHEN Yan,ZHANG Dan-jin,WANG Ting,XIE Jian-shan,ZHANG Yu,YU Xiu-ju,CAO Jing,HE Xiao-yan.Research Progress on the Effect of IGF-1 on Hair Growth of Animals[J].China Animal Husbandry & Veterinary Medicine,2013,40(10):169-172. |
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| Authors: | SHEN Yan ZHANG Dan-jin WANG Ting XIE Jian-shan ZHANG Yu YU Xiu-ju CAO Jing HE Xiao-yan |
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| Institution: | 1. College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China;2. Beijing Vocational College of Agriculture, Beijing 102442, China |
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| Abstract: | The growth of hair of animals is a very complicated process which is influenced by various factors such as heredity,endocrine,nutrition and external conditions.The insulin-like growth factor-1 (IGF-1) is a bioactive peptide which has effect on the proliferation and differentiation of cell, and regulates metabolism. Many researches have also found that the effect of IGF-1 on some cytokines.This paper reviews the progress of IGF-1 in hair/hair growth so as to show the important role of IGF-1 on hair/hair growth. |
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| Keywords: | animal hair/hair growth insulin-like growth factor-1 signaling pathway |
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