抽薹开花抑制因子FLC 表观遗传调控研究进展

FLOWERING LOCUS C（FLC）是植物抽薹开花调控网络中关键的开花决定因子。随着表观遗传学的发展，人们发现组蛋白修饰等表观调控FLC 的表达在植物抽薹开花时间调控中起着非常重要的作用。FLC 的抑制因子或促进因子通过改变组蛋白氨基酸的共价修饰（如乙酰化、甲基化等），影响FLC基因所在区域的染色质重塑，调控FLC 转录表达水平，从而调节植物抽薹开花。本文就近年来国内外对植物抽薹开花关键调控基因FLC 及表观遗传调控其表达研究现状进行了综述，并针对目前研究中存在的问题提出了今后的研究方向和重点。

Research Progress on Epigenetic Regulation of Flowering Repressor FLC

FLOWERING LOCUS C（FLC）is a key deciding factor in regulating plant bolting and flowering network．Along with the development of epigenetics，scientists found that histone modification and other epigenetic regulation of FLC expression played very important role in regulating plant bolting and flowering．Chromatin covalent modification included acetylation and methylation of lysine and arginine．The recent characterization of FLC repressors and activators has shown that some of these regulatory proteins are involved in the covalent modification of FLC chromatin and controlling the flowering time．This paper reviewed the present internal and external status on studying the regulating gene FLC for plant bolting and flowering，and epigenetic regulation and its expression．The paper also provided direction and focus for future studies according the prob lems existing in present research．