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产志贺毒素大肠杆菌流行病学及主要毒力因子研究进展
引用本文:旷代,潘海建,杨筱薇,李赞阳,张建民.产志贺毒素大肠杆菌流行病学及主要毒力因子研究进展[J].中国畜牧兽医,2013,40(8):180-184.
作者姓名:旷代  潘海建  杨筱薇  李赞阳  张建民
作者单位:1. 上海交通大学农业与生物学院, 上海 200240;
2. 华南农业大学兽医学院, 广东广州 510642
基金项目:中国博士后科学基金第50批面上项目(2011M500781);中国博士后科学基金第5批特别资助项目(2012T50419)。
摘    要:产志贺毒素大肠杆菌(Shiga toxin-producing Escherichia coli,STEC) 是一类能引起包括水样腹泻、出血性结肠炎、尿毒综合症等一系列人体疾病的人畜共患肠道致病菌,其感染在世界范围内包括中国都有过暴发流行。文章阐述了STEC O157血清型和非O157血清型的分布特征及流行趋势,同时还对该病的主要毒力因子进行了综述,以期为该病的防控提供科学依据。

关 键 词:产志贺毒素大肠杆菌  流行病学  毒力因子  
收稿时间:2013-01-18

Research Progress on Epidemiology and Major Virulence Factors of Shiga Toxin-producing Escherichia coli
KUANG Dai,PAN Hai-jian,YANG Xiao-wei,LI Zan-yang,ZHANG Jian-min.Research Progress on Epidemiology and Major Virulence Factors of Shiga Toxin-producing Escherichia coli[J].China Animal Husbandry & Veterinary Medicine,2013,40(8):180-184.
Authors:KUANG Dai  PAN Hai-jian  YANG Xiao-wei  LI Zan-yang  ZHANG Jian-min
Institution:1. College of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China;
2. College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
Abstract:Shiga toxin-producing Escherichia coli (STEC) is a group of zoonotic enteric pathogens that can cause a series of human illnesses ranging from watery diarrhea to hemorrhagic colitis and hemolytic uremic syndrome. Infections of the pathogen have outbroken in China and worldwide. The article reviewed the distribution and epidemiological trend of STEC O157 and non-O157. Meanwhile, main virulence factors of the disease were reviewed for the purpose to provide a scientific basis for prevention and control of the disease.
Keywords:Shiga toxin-producing Escherichia coli (STEC)  epidemiology  virulence factor  
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