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Hemoglobin variant common to Chinese and North American Indians: alpha-2-beta-22 Glu-Ala
Authors:R W Blackwell  C S Liu  H J Yang  C C Wang  J T Huang
Abstract:An electrophoretically slow hemoglobin variant, in which the structural change involves the replacement of a glutamyl residue by alanyl at position beta-22, was reported in two groups of North American Indians: hemoglobin-G Coushatta, in Alabama-Coushatta Indians in Texas; and hemoglobin-G Saskatoon, in descendants of Santee Indians living in Canada. Hemoglobin-G Hsin-Chu, found in Taiwan in a Chinese from the northern Chinese province of Liaoning, is now shown to have the same structural anomaly.
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