恩诺沙星对鲫鱼过氧化氢酶活性的影响

研究了恩诺沙星对鲫鱼鳃、肝脏、肾脏组织过氧化氢酶(CAT)活性的影响。急性毒性测定表明,恩诺沙星对鲫鱼的96 h LC50为21.38 mg/L。较低浓度的恩诺沙星会使各组织CAT活性受到一定诱导,随着试验时间的延长而增加。而较高浓度恩诺沙星会使各组织CAT活性随着试验时间的延长而下降。结果表明,恩诺沙星暴露所引起的酶活性变化与暴露浓度和暴露时间有一定的相关性。

Effects of Enrofloxacin on Activities of CAT in Carassius auratus

Effects of different concentrations of Enrofloxacin on the activities of catalase(CAT)in gill,liver and nephrectomy of Carassius auratus are studied.Aeute toxicity test showed that the 96 h LC_(50) of Enrofloxacin to Carassius auratus was 21.38 mg/L.Induction of the enzymes in all tested tissues occurred in the initial exposure days,and then the enzyme activities increase with extension of exposure time,when Carassius auratus exposure to the lowest concentrations(1.5 mg/L,2.5mg/L).And the enzyme activities decreased with extension of exposure times in the highest concentrations(15 mg/L,20 mg/L).The results suggested that the enzyme activities correlated to the Enrofloxacin concentrations and the exposure time.