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Some characteristics of the antibodies involved in allergic skin reactions of the horse to biting insects |
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| Institution: | 1. School of Civil Engineering, Central South University, Changsha 410075, China;2. School of Civil Engineering and Architecture, Xiamen University of Technology, Xiamen 361024, China;3. School of Civil and Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore;1. Centre for Product Design and Manufacturing, Indian Institute of Science, Bangalore, India;2. AIIMS, New Delhi, India |
| Abstract: | Active skin tests were carried out on a horse with sweet itch using extracts of various biting insects and the resulting reactions compared with those produced when rabbit anti-human IgE was injected intradermally into a normal horse. The horse with sweet itch produced a large reaction to an extract of Culicoides which was similar to those produced by anti-human IgE. Absorption of serum from an allergic horse with anti-human IgE reduced its ability to sensitize skin of a normal horse to challenge with the extract of Culicoides. Passive transfer of allergic horse serum to guinea-pig skin gave significant reactions when challenged after a latent period of 4 h but not after 24 h. |
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