| 应用端粒长度推断个体年龄的研究进展 |
| |
| 引用本文： | 杨啸枫,杨曙明,汤晓艳,于洪侠,王迪,孙丰梅.应用端粒长度推断个体年龄的研究进展[J].中国畜牧兽医,2008,35(9):41-44. |
| |
| 作者姓名： | 杨啸枫 杨曙明 汤晓艳 于洪侠 王迪 孙丰梅 |
| |
| 作者单位： | 1.中国农业科学院农业质量标准与检测技术研究所，北京 100081；2.河北北方学院食品科学系，张家口 075131 |
| |
| 基金项目： | 中央级公益性科研院所基本科研业务费专项
|
| |
| 摘 要： | 细胞衰老机制是细胞生物学研究的一个重要课题。随着端粒及端粒酶与细胞衰老和年龄增长关系的揭示，端粒长度的缩短已经成为细胞衰老和年龄增长的生物学标志之一。作者首先介绍了端粒和端粒酶的结构、功能，进而分析其与细胞衰老、年龄增长的关系，并对端粒和端粒酶在年龄推断中的应用研究加以综述。
|
| 关 键 词： | 端粒 端粒酶 细胞衰老 年龄推断 |
The Progress in Individual Age Estimation by the Length of Telomere |
| |
| YANG Xiao-feng,YANG Shu-ming,TANG Xiao-yan,YU Hong-xia,WANG Di,SUN Feng-mei.The Progress in Individual Age Estimation by the Length of Telomere[J].China Animal Husbandry & Veterinary Medicine,2008,35(9):41-44. |
| |
| Authors: | YANG Xiao-feng YANG Shu-ming TANG Xiao-yan YU Hong-xia WANG Di SUN Feng-mei |
| |
| Institution: | 1.Institute of Quality Standard and Testing Technology for Agro Product,CAAS,Beijing 100081,China;2.Food Science Department of Hebei North University,Zhangjiakou 075131,China |
| |
| Abstract: | The mechanism of cellular senescence is an important issue in cell biology. With the development of study on relationship between telomere-telomerase and cell senescence/aging, the telomere shortening has become one of the biological marks of cell aging and age growth. This article firstly introduced the structure and function of telomere and telomerase, then analyzed the relationship between them and cell aging or the growth of age, finally summarized the application progress in age estimation based on telomeres and telomerase. |
| |
| Keywords: | telomere telomerase cellular aging age estimation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国畜牧兽医》浏览原始摘要信息 |
| 点击此处可从《中国畜牧兽医》下载免费的PDF全文 |
|
