几种常用药物对淡水黑鲨的急性毒性及药浴试验

为掌握淡水黑鲨疾病防治的科学用药量,以生石灰、硫酸铜硫酸亚铁合剂（5∶2）、强氯精、敌百虫对淡水黑鲨鱼苗进行急性毒性试验,并用氯化钠、高锰酸钾、聚维酮碘对其进行药浴试验。结果表明,生石灰、硫酸铜硫酸亚铁合剂（5∶2）、强氯精、敌百虫对淡水黑鲨的安全浓度（SC）分别为60.290、0.057、0.130、0.400 mg/L,其毒性大小依次为：硫酸铜硫酸亚铁合剂（5∶2）〉强氯精〉敌百虫〉生石灰;而药浴试验结果表明,氯化钠药浴浓度以2.0%～2.5%为宜,高锰酸钾和聚维酮碘则按常用量使用。

Assessment of acute toxicity levels and dipping bath test for some commonly-used drugs on Pangasias sutchi

The present experiment was conducted to study the effects of different drug formulations on controlling the diseases of Pangasias sutchi in fresh water.The four drug formulations,viz.,CaO;CuSO4∶FeSO4（5∶2）;trichloroisocyanuric acid（TCCA） and dipterex,were given to Pangasias sutchi juveniles（4.5-7.3 cm in body length）,and acute toxicity was determined at 24.9-27.8℃ of water temperature,7.5-8.3 of pH and 4.0-5.8 mg/L of dissolved oxygen.The dipping bath of NaCl,KMnO4 and polyvenyl pyrrolidone（PVP） on Pangasias sutchi was carried out.The descending order of median lethal concentrations of drugs,affecting the juveniles,after 96 hours was as follows： CuSO4∶FeSO4（5∶2）DipterexTCCACaO,with safe concentrations of 0.057,0.400,0.130,60.290 mg/L,respectively.In dipping bath experiment,the suitable NaCl concentration was found to be ranged from 2-2.5%,and the PVP and KMnO4 may be used in normal dosage（1.0-1.5,15-20 mg/L） in the dipping bath.