| 基因疫苗在畜禽传染病中的应用及前景 |
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| 引用本文： | 梁雪芽,李建荣,于涟,方维焕. 基因疫苗在畜禽传染病中的应用及前景[J]. 动物医学进展, 2001, 22(3): 20-24 |
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| 作者姓名： | 梁雪芽 李建荣 于涟 方维焕 |
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| 作者单位： | 浙江大学动物预防医学研究所, |
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| 基金项目： | 国家“8 63”高科技项目 (1 0 1 -j99-0 2 ) |
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| 摘 要： | 介绍了基因疫苗的免疫学特性、增强免疫效力策略以及在畜禽传染病领域中应用的最新动态，展望了其广阔的应用前景，并提出了基因疫苗在应用过程中产生的一系列有待于进一步解决的问题，从而为畜禽传染病的防制提供了新思路和新途径。
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| 关 键 词： | 基因疫苗 免疫学特性 真核表达载体 免疫功能预处理 畜禽传染病 应用 |
| 文章编号： | 1007-5038(2001)03-0020-05 |
| 修稿时间： | 2001-02-26 |
Progress on application and prospect of genetic vaccine against infectious diseases in animals |
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| LIANG Xue ya,LI Jian rong,YU Lian,FANG Wei huan. Progress on application and prospect of genetic vaccine against infectious diseases in animals[J]. Progress In Veterinary Medicine, 2001, 22(3): 20-24 |
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| Authors: | LIANG Xue ya LI Jian rong YU Lian FANG Wei huan |
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| Abstract: | Genetic vaccine, as it is commonly known today, is an antigen encoding plasmid that upon introduction into body is capable of directing in vivo expression of that protein and inducing antigen specific immune responses. In this paper, the immunological characterization, advantage and newly application of DNA vaccines were reviewed. To obtain more satisfactory immune efficacy, many effective methods were also discussed here. However, some problems such as security, stability and mechanism of DNA vaccine remain to be solved. This information could be very important for future control of infectious diseases. |
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| Keywords: | genetic vaccination DNA vaccine infectious disease application |
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