海藻硫酸多糖抗氧化活性研究进展

本文就海藻硫酸多糖（SPS）的结构特征、制备，抗氧化机制及影响因素进行了较为详细的阐述。众多研究表明，SPS是从海藻中提取的一类生物活性多糖，是多糖分子链中单糖分子的部分羟基被硫酸根取代而形成的；它能有效地清除自由基，还能与金属离子鳌合，抑制脂质过氧化作用，具有显著抗氧化活性；制备粗多糖主要采用水提醇沉法，用离子交换、凝胶渗透和亲和层析法进行纯化；影响SPS抗氧化活性的因素主要有硫酸多糖的来源、多酚含量、相对分子质量大小以及硫酸基的含量与位置等。

Research Progress on Antioxidant Activity of Algae Sulphated Polysaccharides

In this paper, the structural characteristics, preparation, antioxidant mechanism and influence factors of Sulphated polysaccharides （SPS） were described in detail. Many researches indicated that, SPS was a kind of biological activity polysac- charide, extracted from seaweed, which formed by the displacement of some hydroxyl groups monosaccharide molecules with sulphate acid groups in polysaccharide molecules chains; SiX3 could effectively clear free radical, chelate metallic ire and had significant antioxidant activity; crude polysaccharide was extracted by ethanol, purified using ion - exchange chromatography, gelflltration techniques and affinity chromatography; the influence factors of SPS antioxidant activity were the source of SIX3, polyphenol content, relative molecular mass and sulphate acid groups content and position.