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女性不孕患者解脲支原体、人型支原体和抗子宫内膜抗体水平的检测
引用本文:邓超干 沈彦珍 蔡钦泉 林小丹 卢文深 蔡毅华. 女性不孕患者解脲支原体、人型支原体和抗子宫内膜抗体水平的检测[J]. 湛江医学院学报, 2005, 23(5): 521-522
作者姓名:邓超干 沈彦珍 蔡钦泉 林小丹 卢文深 蔡毅华
作者单位:广东省深圳市罗湖区人民医院检验科,广东,深圳,518001;广东省深圳市罗湖区人民医院生殖中心,广东,深圳,518001
摘    要:目的:研究女性不孕与解脲支原体(UU)、人型支原体(MH)感染和抗子宫内膜抗体(AEMAb)之间的关系。方法:采用培养法分别对139例原发性和167例继发性不孕患者的官颈分泌物进行UU、MH检测;采用ELISA法检测血清中AEMAb。同时选择健康已孕妇女102人作为对照组。结果:原发性及继发性不孕组UU、MH感染率及AEMAb阳性率与对照组比较差异均有显著性(P〈0.01);原发不孕组与继发不孕组UU、MH感染率、AEMAb阳性率相比差异无显著性(P〉0.05);不孕组中支原体感染阳性患者AEMAb阳性率明显高于支原体阴性患者(P〈0.01)。结论:女性不孕与生殖道支原体感染及免疫因素有关,且AEMAb的产生与支原体感染有关。

关 键 词:不孕症  解脲支原体  人型支原体  抗子宫内膜抗体
文章编号:1005-4057(2005)05-0521-02
收稿时间:2005-01-22
修稿时间:2005-04-15

Genital tract infection of Ureaplasma urealyticum and Mycoplasma hominis and serum anti-endometrial antibody in infertile women
Deng ChaoGan;Shen YanZhe;Cai QinQuan;Lin XiaoDan;Lu WenShen;Cai YiHua. Genital tract infection of Ureaplasma urealyticum and Mycoplasma hominis and serum anti-endometrial antibody in infertile women[J]. Journal of Guangdong Medical College, 2005, 23(5): 521-522
Authors:Deng ChaoGan  Shen YanZhe  Cai QinQuan  Lin XiaoDan  Lu WenShen  Cai YiHua
Abstract:Objective: To study the relationship between Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) infection and anti-endometrial antibody (AEMAb)in infertile women. Methods: UU and MH in cervical secretions and serum AEMAb level in 139 women with primary infertility, 167 with secondary infertility and 102 controls were determined by culture and ELISA, respectively. Results: Positive rates of UU, MH and AEMAb in infertile group were significantly higher than that in control group (P<0.01), but there were no statistical differences between primary and secondary infertility (P>0.05). The detection rate of AEMAb in infertile patients with mycoplasma were superior to that without mycoplasma (P<0.01). Conclusion: Genital tract infection of UU and MH and immunological factor could be related to female infertility. AEMAb formation may be induced by mycoplasma infection.
Keywords:infertility    Ureaplasma urealyticum    Mycoplasma hominis    anti-endometrial antibody
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