Vertical transmission of Neospora caninum in BALB/c mice in both acute and chronic infection |
| |
Authors: | Omata Y Nidaira M Kano R Kobayashi Y Koyama T Furuoka H Maeda R Matsui T Saito A |
| |
Institution: | Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan. yomata@obihiro.ac.jp |
| |
Abstract: | To examine the frequency of congenital infection by Neospora caninum, BALB/c mice were inoculated intraperitoneally with tachyzoites of N. caninum either during pregnancy (Group 1) or 4 weeks or more before pregnancy (Group 2). Further, the mice inoculated during pregnancy were bred at 4 weeks or more after delivery to form Group 3. Congenital transmission was observed in 76% of the neonates of the mice in Group 1 and in 50% of the neonates of the mice in Group 2. Interestingly, congenital transmission was observed in 86% of the neonates from Group 3. These results suggest that chronically-infected BALB/c mice efficiently transmit N. caninum infection to their offspring. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|