| 小鹅瘟马源高免血清的制备及应用 |
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| 引用本文： | 李琳,邵洪泽,任科研,毛文智,许志林,姚新华.小鹅瘟马源高免血清的制备及应用[J].动物医学进展,2010,31(9). |
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| 作者姓名： | 李琳 邵洪泽 任科研 毛文智 许志林 姚新华 |
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| 作者单位： | 吉林省畜牧兽医科学研究院,吉林长春,130062 |
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| 摘 要： | 采用JLDA株小鹅瘟抗原,高免马匹后经采血精制可获得滴度为1∶64～1∶128的抗小鹅瘟高免血浆。通过胃蛋白酶消化-硫酸铵盐析的工艺,得到小鹅瘟马源高免血清。按0.5 mL/羽剂量共预防雏鹅52.48万羽,按1 mL/羽～3 mL/羽剂量共治疗感染雏鹅5.66万羽,证实该抗血清效价高,对雏鹅的预防保护率为95.58%,对感染雏鹅的治愈率为92.87%,表明对小鹅瘟防治安全高效。马采血量大,成本低,同时有效地避免了同源动物间其他疫病的感染和强毒的散播,较之用鹅作为血清来源动物经济和社会效益显著。
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| 关 键 词： | 小鹅瘟 鹅细小病毒 马源高免血清 制备 应用 |
Preparation and Application of Hyperimmune Serum Against Goose Parvovirus from Horse |
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| LI Lin,SHAO Hong-ze,REN Ke-yan,MAO Wen-zhi,XU Zhi-lin,YAO Xin-hua.Preparation and Application of Hyperimmune Serum Against Goose Parvovirus from Horse[J].Progress In Veterinary Medicine,2010,31(9). |
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| Authors: | LI Lin SHAO Hong-ze REN Ke-yan MAO Wen-zhi XU Zhi-lin YAO Xin-hua |
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| Institution: | LI Lin,SHAO Hong-ze,REN Ke-yan,MAO Wen-zhi,XU Zhi-lin,YAO Xin-hua(Institute of Animal Husbandry and Veterinary Science of Jilin,Changchun,JiLin,130062,China) |
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| Abstract: | Hyperimmune serum against JLDA strain of goose parvovirus was obtained from horses.52.48 million goslings were immunized for prevention by injecting 0.5 mL of the hyperimmune serum per goose,and 5.66 million infected goslings were injected 1 mL-3 mL per goose for treatment.The protection rate was 95.58%,and the cure rate was 92.87%.The results showed that the hyperimmune serum is a highly effective and safe agent.Hyperimmune serum obtained from horses not only could effectively avoid the homologous animals ... |
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| Keywords: | Gosling plague Goose parvovirus virus hyperimmune serum from horse preparation application |
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