Pheno- and genotypic characterization of Pasteurella multocida isolated from cats,dogs and rabbits from Brazil |
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| Institution: | 1. National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China;2. College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei 430070, China;3. College of Veterinary Medicine, Agricultural and Animal Husbandry College of Tibet University, Nyingchi, Tibet 860000, China;4. Institute of Animal Husbandry and Veterinary, Hubei Academy of Agricultural Science, Wuhan, Hubei 430064, China;5. Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan, Hubei 430070, China;6. The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, Hubei 430070, China;7. Key Laboratory of development of veterinary diagnostic products, Ministry of Agriculture, Wuhan, Hubei 430070, China |
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| Abstract: | Pasteurella multocida is the causative agent of many diseases of economic importance in veterinary medicine and is characterized by high zoonotic potential. Pet animals can be infected and play a major role as carriers. This study aimed to characterize the genetic diversity of P. multocida isolated from dogs, cats and rabbits, and to evaluate their antimicrobial susceptibility profiles. A total of 620 animals were studied; 51 were positive for P. multocida and 92 strains were isolated. 60.9% of the strains belonged to the capsular type A, while the remaining were classified as non-typeable. The hgbA, ptfA, sodC, tadD and hsf2 genes were more frequent among the rabbit strains. Sulfonamides and cotrimoxazole presented the highest resistance rate, followed by erythromycin. PFGE clustered strains according to host species. Our results indicate that P. multocida from companion animals carry several virulence factors and are resistant to antimicrobials commonly used in human and veterinary medicine. |
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| Keywords: | Virulence genes Resistance PFGE |
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