Antimicrobial resistance and virulence profiles of Enterococcus spp. isolated from horses in korea |
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| Affiliation: | 1. Department of Veterinary Microbiology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Republic of Korea;2. Department of Animal Science and Technology, College of Biotechnology and Natural Resource, Chung-Ang University, 2nd Campus, Anseong 456-756, Republic of Korea;3. Animal and Plant Quarantine and Inspection Agency (QIA), Anyang 430-757, Republic of Korea;1. Division of Gynecology Oncology, Department of Obstetrics and Gynecology, University of Toronto, Toronto, Canada;2. Princess Margaret Hospital, University of Toronto, Toronto, Canada;3. Department of Medical Imaging, University of Toronto, Toronto, Canada;4. Department of Clinical Programs, Cancer Imaging Program, Cancer Care Ontario, Canada;5. Department of Radiation Medicine, University of Toronto, Toronto, Canada;1. United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan;2. Department of Veterinary Medicine, Faculty of Applied Biological Science, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan;3. Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan;1. Department of Pediatrics, Hans Christian Andersen Children''s Hospital, Odense University Hospital, Odense, Denmark;2. The Danish Twin Registry, University of Southern Denmark, Odense, Denmark |
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| Abstract: | Antimicrobial-resistant (AR) enterococci have emerged as leading nosocomial pathogens. Transmission of AR Enterococci from animals to humans has been demonstrated. However, there is limited information on the transmission of enterococci from horses to humans. To address this issue, we characterized 260 enterococci isolated from horse-associated samples in Korea in 2013 based on their AR profiles and virulence traits. AR profiling revealed an average ratio of AR enterococci of 23.8%. Seven isolates (2.7%) were multidrug-resistant Enterococcus faecalis. Most tetracycline-resistant enterococci harbored either tetM or tetL or both genes; genes conferring resistance to other antimicrobials were detected at low rates. Biofilm formation and gelatinase activity were observed in 51.1% and 47.7% of isolates, respectively; most were E. faecalis harboring the gelE gene. Evidence of transmission of AR enterococci between horses and their environments was provided by pulsed-field gel electrophoresis, and highlights the risk of AR enterococcus transmission to horse riders and handlers through close contact. |
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| Keywords: | Enterococci Antimicrobial resistance Virulence Horses Cross-transmission |
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