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Growth enhancement following dietary delivery of recombinant porcine somatotropin to diploid and triploid coho salmon (Oncorhynchus kisutch)
Authors:Ewen McLean  Edward M. Donaldson  Emin Teskeredzic  Lawrence M. Souza
Affiliation:(1) Biotechnology, Genetics & Nutrition Section, West Vancouver Laboratory, 4160 Marine Drive, West Vancouver, B.C., V7V 1N6, Canada;(2) Ruder Boskovic Institute, Center for Marine Research, Zagreb, Croatia;(3) Amgen Inc., 1900 Oak Terrace Lane, Thousand Oaks, CA, 91320, U.S.A.;(4) Department of Fisheries and Oceans, West Vancouver Laboratory, 4160 Marine Drive, West Vancouver, B.C., V7V 1N6, Canada
Abstract:Diploid (2n) and triploid (3n) coho salmon were fed upon control (diet 1), recombinant porcine somatotropin (rpST)-supplemented (diet 2; 20 μg rpST/g body wt/day) or rpST/antacid/detergent-containing feed (diet 3; 20, 100 &; 20 μg/g body wt/day respectively) for 16 wk. Fish were weighed and measured bimonthly and their relative performances assessed. By wk 4, 2n and 3n groups fed upon diet 2 were significantly heavier and longer than control 2n fish. At the termination of the trial, diet 3 fed animals were greater in weight than all other treatment groups. Diet 3 salmon also returned better feed conversion efficiencies than either diet 1 or 2 groups. RpST therapy induced a 28.7% and 60.2% increase in group wt for 3n diet 2/3 coho versus (?vs?) controls. Likewise, 2n rpST-treated fish increased wt ?vs?2n control coho by 17% and 50% respectively over the same period. No differences were recorded between groups for body moisture, but diet 2, 3n and both diet 3 groups exhibited decreased condition factors when compared to control fish (p ≤ 0.05).
Keywords:growth acceleration  salmonids  oral administration  somatotropin  triploid  diploid
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