Changes of plasma and myocardial calcitonin gene-related peptide in myocardial stunning rats |
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Authors: | WU Hong-chao QIAN Xue-xian LI Li-ping |
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Affiliation: | Department of Cardiology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China |
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Abstract: | AIM: To investigate changes of calcitonin gene-related peptide(CGRP) in myocardial stunning rats. METHODS: Rat in vivo myocardial stunning model was used. CGRP content in plasma and myocardium were determined by radioimmunoassay. RESULTS: Plasma level of CGRP increased significantly (P<0.01), but in left ventricular myocardium CGRP decreased obviously (P<0.05) in myocardial stunning group compared with the control group. CONCLUSION: CGRP content in the left ventricular myocardium was negatively correlated with plasma CGRP. |
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Keywords: | Myocardium Calcitonin gene-related peptide Rats |
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