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Effect of lipopolysaccharide on apoptosis of human umbilical vein endothelial cells
Authors:SONG Yong  MAO Bao-ling  WANG Jian-chun
Affiliation:1. Department of Respiratory Medicine, Nanjing General Hospital of Nanjing Command, Nanjing 210002; 2. Institute of Respiratory Disease, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
Abstract:AIM: To explore the mechanism of lipopolysaccharide (LPS) on vascular endothelial cell(VEC) damage. METHODS: By using cytometry techniques, we studied the effects of LPS on apoptosis of human umbilical vein endothelial cells (HUVECs) in vitro. RESULTS: LPS was able to induce apoptosis of HUVECs in a time-dose-dependent fashion.CONCLUSION:Apoptosis might play a role in LPS-induced damage of vascular endothelial cells.
Keywords:Lipopolysaccharides  Endothelium   vascular  Cells  Lung  
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