Effect of lipopolysaccharide on apoptosis of human umbilical vein endothelial cells |
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Authors: | SONG Yong MAO Bao-ling WANG Jian-chun |
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Affiliation: | 1. Department of Respiratory Medicine, Nanjing General Hospital of Nanjing Command, Nanjing 210002; 2. Institute of Respiratory Disease, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China |
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Abstract: | AIM: To explore the mechanism of lipopolysaccharide (LPS) on vascular endothelial cell(VEC) damage. METHODS: By using cytometry techniques, we studied the effects of LPS on apoptosis of human umbilical vein endothelial cells (HUVECs) in vitro. RESULTS: LPS was able to induce apoptosis of HUVECs in a time-dose-dependent fashion.CONCLUSION:Apoptosis might play a role in LPS-induced damage of vascular endothelial cells. |
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Keywords: | Lipopolysaccharides Endothelium vascular Cells Lung |
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