Protective effect of Spirulina fusiformis on chemical-induced genotoxicity in mice |
| |
| Authors: | Premkumar K Abraham S K Santhiya S T Ramesh A |
| |
| Institution: | Department of Genetics, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai 600-113, India. pkumpati@yahoo.co.in |
| |
| Abstract: | Spirulina fusiformis given by oral route to mice at doses of 250, 500 and 1000 mg kg(-1) significantly inhibit the genotoxicity induced by cisplatin and urethane. In addition, a significant reduction in the extent of lipid peroxidation with concomitant increase in the liver enzymatic (GPx, GST, SOD, CAT) and non-enzymatic (reduced glutathione) antioxidants were observed. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
