Leaching of four different antibacterials from oil- and alginate-coated fish-feed pellets |
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| Authors: | K Duis V Inglis M C M Beveridge C Hammer |
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| Institution: | Institute of Hydrobiology and Fisheries, University of Hamburg, Hamburg, Germany;Institute of Aquaculture, University of Stirling, Stirling, United Kingdom |
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| Abstract: | Leaching of oxytetracycline, oxolinic acid, amoxycillin and the potentiated sulphonamide trimethoprim/ sulphamethoxazote (TMP/SMX) from surface-coated fish-feed pellets, surrounded with either cod liver oil or with calcium-alginate, was investigated. Despite the low water temperature (12°C), losses of amoxycillin, oxytetracycline and TMP/SMX from the oil-coated feed were high with 41.6-67.3% of the drugs lost after 15 min immersion. By contrast, less than 20% of oxolinic acid was lost within the same interval. When calcium-alginate was used, leaching rates were found to be considerably lower. Losses of TMP/SMX. amoxycillin and oxytetracycline ranged from 6.3 to 24.1% within 15 min. Leaching of oxolinic acid was completely prevented by the alginate. |
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