| 传染性法氏囊病病毒感染对鸡脾脏B淋巴细胞的影响 |
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| 引用本文： | 马晓丽 毛炳宇. 传染性法氏囊病病毒感染对鸡脾脏B淋巴细胞的影响[J]. 山东农业科学, 1998, 0(1): 17-20 |
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| 作者姓名： | 马晓丽 毛炳宇 |
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| 摘 要： | 从口腔和泄殖腔对ＳＰＦ鸡人工感染传染性鸡法氏囊病病毒（ＩＢＤＶ），于感染后１２、２４、３６、４８小时观察脾脏组织Ｂ淋巴细胞的病理学变化。并通过核酸电泳观察了感染后脾脏组织细胞ＤＮＡ的变化情况。研究结果表明，ＩＢＤＶ感染仔鸡后，可诱导仔鸡脾脏Ｂ淋巴细胞凋亡。
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| 关 键 词： | IBDV B淋巴细胞 凋亡 |
Influence of Infection with Infectious Bursal Disease Virus on Splenic B Lymphocytes in Chicken |
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| Abstract: | Infectious bursal disease virus (IBDV)was artificially infected to SPF chicken through mouth and cloaca.After 12,24,36 and 48 hours,pathological changes of splenic B lymphocytes were observed by light microscopy,electron microscopy and imunofluorescence microscopy.Also,DNA changes of splenic cells were observed by nuclear electrophoresis.The result showed that IBDV induce apoptosis of splenic B lymphocytes. |
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| Keywords: | Chicken IBDV B lymphocyte apoptosis |
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