| 仔猪大肠杆菌病三价蜂胶灭活疫苗猪体血清抗体消长规律 |
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| 引用本文： | 范忠军,柴虹,朱万光,李士成. 仔猪大肠杆菌病三价蜂胶灭活疫苗猪体血清抗体消长规律[J]. 吉林畜牧兽医, 2007, 28(8): 11-12,15 |
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| 作者姓名： | 范忠军 柴虹 朱万光 李士成 |
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| 作者单位： | 山东滨州华宏生物制品有限责任公司研究所,山东滨州,256600;山东滨州华宏生物制品有限责任公司研究所,山东滨州,256600;山东滨州华宏生物制品有限责任公司研究所,山东滨州,256600;山东滨州华宏生物制品有限责任公司研究所,山东滨州,256600 |
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| 摘 要： | 采用大肠杆菌C83549(O149:K88ac)、C83644(O68:K99)、C83710(O9:987P)菌株制备抗原,以蜂胶为佐剂,研制仔猪大肠杆菌病三价蜂胶灭活疫苗,疫苗成品检验均符合相关要求。将疫苗免疫妊娠母猪并用凝集试验测定其所产仔猪的抗体消长规律,并研究疫苗免疫保护相关性。结果表明:妊娠母猪产前40d和15d各免疫1次所产仔猪母源抗体效价较高,仔猪在整个哺乳期都可以得到保护。同时也可运用产前30d和10d进行免疫接种方法。
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| 关 键 词： | 大肠杆菌 蜂胶疫苗 妊娠母猪 消长规律 |
| 文章编号： | 1672-2078（2007）08-0011-03 |
| 收稿时间： | 2007-07-09 |
| 修稿时间： | 2007-07-09 |
Rising and Falling Rule of Serum Antibodies in Pigs Vaccinated with E. Coli Trivalent Inactivated Vaccine in Propolis-adjuvant for Newborn Piglets |
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| FAN Zhong-jun,CHAI Hong,ZHU Wan-guang,LI Shi-cheng. Rising and Falling Rule of Serum Antibodies in Pigs Vaccinated with E. Coli Trivalent Inactivated Vaccine in Propolis-adjuvant for Newborn Piglets[J]. Jilin Animal Science and Veterinary Medicine, 2007, 28(8): 11-12,15 |
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| Authors: | FAN Zhong-jun CHAI Hong ZHU Wan-guang LI Shi-cheng |
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| Affiliation: | Binzhou HuaHong Biological Products Co, Ltd. Institute, Binzhou Shandong 256600 |
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| Abstract: | E. Coli trivalent inactivated vaccine for newborn piglets was developed using C83549 (O149: K88ac),C83644 (O68: K99),C83710 (O9: 987P) bacterium strains as its antigen and in propolis-adjuvant. After a series of detecting tests,five batches of the vaccine produced in lab were proved harmless and potent. Agglutination test was applied to examing antibody level of the piglets. The results showed that maternal antibody titer of suckling pigs produced by sow vaccinated two times was higher,and the piglets can be protected from E.coli attacking during nursing period. |
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| Keywords: | E.Coli propolis-adjuvant vaccine sow rising and falling law |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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