Antidiabetic properties of aqueous barks extract of Parinari excelsa in alloxan-induced diabetic rats |
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| Authors: | Ndiaye M Diatta W Sy A N Dièye A M Faye B Bassène E |
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| Affiliation: | Laboratoire de Pharmacologie, Faculté de Médecine, de Pharmacie et d'Odontostomatologie, Université Cheikh Anta Diop, Dakar, Senegal. mndiaye10@sentoo.sn |
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| Abstract: | The aqueous extract of the Parinari excelsa barks at doses of 100 and 300 mg/kg/day for 7 days has a significant antihyperglycemic effect on alloxan-induced diabetic rats. At the same dose the acute oral administration of aqueous extract of the P. excelsa barks (100 and 300 mg/kg) induced a significant decrease of blood glucose on glucose-loaded normoglycaemic rats. Our results seem to confirm the rational bases for its use in traditional medicine. |
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| Keywords: | Parinari excelsa Antidiabetic Alloxanic rats |
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