Control of experimental autoimmune encephalomyelitis by T cells responding to activated T cells |
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Authors: | A W Lohse F Mor N Karin I R Cohen |
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Institution: | Weizmann Institute of Science, Department of Cell Biology, Rehovot, Israel. |
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Abstract: | T cell vaccination against experimental autoimmune disease is herein shown to be mediated in part by anti-ergotypic T cells, T cells that recognize and respond to the state of activation of other T cells. The anti-ergotypic response thus combines with the previously shown anti-idiotypic T cell response to regulate autoimmunity. |
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