The application of antimicrobial peptides as growth and health promoters for swine |
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| Authors: | Hao Xiao Fangyuan Shao Miaomiao Wu Wenkai Ren Xia Xiong Bie Tan Yulong Yin |
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| Affiliation: | 1.Observation and Experiment Station of Animal Nutrition and Feed Science in South-Central China, Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture, Chinese Academy of Sciences,Changsha,China;2.University of the Chinese Academy of Sciences,Beijing,China;3.Department of Microbiology, Molecular Genetics, and Immunology,University of Kansas Medical Center,Kansas City,USA;4.Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety,Wuhan Polytechnic University,Wuhan,China |
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| Abstract: | With the widespread ban on the use of antibiotics in swine feed, alternative measures need to be sought to maintain swine health and performance. Antimicrobial peptides (AMPs) are part of the nonspecific defense system and are natural antibiotics produced by plants, insects, mammalians, and micro-organisms as well as by chemical synthesis. Due to their broad microbicidal activity against various fungi, bacteria and enveloped viruses, AMPs are a potential alternative to conventional antibiotics for use in swine production. This review focuses on the structure and mechanism of action of AMPs, as well as their effects on performance, immune function and intestinal health in pigs. The aim is to provide support for the application of AMPs as feed additives replacing antibiotics in swine nutrition. |
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| Keywords: | Antimicrobial peptides Antibiotics Applications Swine |
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