Lipoprotein cholesterol and triglyceride concentrations associated with dog
body condition score; effect of recommended fasting duration on sample concentrations in
Japanese private clinics |
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Authors: | Shiho USUI Hidemi YASUDA Yuzo KOKETSU |
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Institution: | 1)School of Agriculture, Meiji University, 1–1–1 Higashi-mita, Tama-ku, Kawasaki, Kanagawa 214–8571, Japan;2)Spectrum Lab Japan, 1–5–22–201 Midorigaoka, Meguro-ku, Tokyo 152–3304, Japan |
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Abstract: | The objectives of this study were to survey clinics’ guidance about recommended
fasting duration (FD) prior to lipoprotein analysis, and to characterize lipoprotein
cholesterol and triglyceride concentrations in obese and overweight dogs categorized on
the basis of the 5-point body condition score (BCS) scale. A dataset was created from
lipoprotein analysis medical records of 1,538 dogs from 75 breeds in 354 clinics from 2012
to 2013. A phone survey was conducted to obtain the clinics’ FD. Two-level linear
mixed-effects models were applied to the data. Over 50% of the clinics said they
recommended fasting for 12 hr or more. Dogs in clinics with FD 12 hr or more had lower
chylomicron triglyceride concentrations than those in clinics with FD less than 8 hr
(P=0.05). Mean (± SEM) BCS at sampling was 3.7 ± 0.02. Obese and
overweight dogs had higher very low density lipoprotein (VLDL) and high density
lipoprotein (HDL) cholesterol and triglyceride concentrations than ideal dogs
(P<0.05), but no such difference was found for low density
lipoprotein cholesterol and triglyceride concentrations (P≥0.07). Across
all BCS, as dog age rose from 0 to 8 years old, HDL cholesterol concentrations decreased
by 13.5 mg/dl, whereas VLDL triglyceride concentrations increased by 81.7
mg/dl (P<0.05). In conclusion, FD of 8 hr or less
may affect lipoprotein lipid concentrations. Obese and overweight dogs were characterized
as having high VLDL and HDL cholesterol and triglyceride concentrations. |
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Keywords: | body condition score canine epidemiology lipids lipoprotein |
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