| 脑心安片质量标准研究 |
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| 引用本文： | 张莹,尹建元,刘继华,李艳艳,李巍,孟勤.脑心安片质量标准研究[J].特产研究,2011,33(1):31-35. |
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| 作者姓名： | 张莹 尹建元 刘继华 李艳艳 李巍 孟勤 |
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| 作者单位： | 1. 吉林大学药学院天然药物化学教研室,长春,130021
2. 吉林大学药学院药学试验中心,长春,130021 |
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| 摘 要： | 建立脑心安片的质量标准。对脑心安片中丹参、葛根、川芎药材采用薄层色谱法进行定性鉴别；采用高效液相色谱法对本品三七中所含三七皂苷R1和人参皂苷Rg1、Rb1进行定量检测。薄层鉴别阴性无干扰，具有良好鉴别特征；R1、Rg1和Rb1分别在0．18～1．66μg、0．606～5．454μg和0．576～5．193μg范围内线性关系良好；平均回收率分别为99．37％、103．64％和98．14％。建立的方法专属性强、重复性良好，为脑心安片的质量检测控制提供依据。
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| 关 键 词： | 脑心安片 质量标准 薄层色谱法 高效液相色谱法 |
Study on Quality Standards of Naoxin' an Tablets |
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| ZHANG Ying,YIN Jian-yuan,LIU Ji-hua,LI Yan-yan,LI Wei,MENG Qin.Study on Quality Standards of Naoxin' an Tablets[J].Special Wild Economic Animal and Plant Research,2011,33(1):31-35. |
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| Authors: | ZHANG Ying YIN Jian-yuan LIU Ji-hua LI Yan-yan LI Wei MENG Qin |
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| Institution: | (2※) (1.Department of NaturaL PharmaceuticaL Chemistry,CoLLege of Pharmacy,Jilin University,Changchun 130021,China; 2.ExperimentaL Center of Pharmacy,CoLLege of Pharmacy,Jilin University,Changchun 130021,China) |
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| Abstract: | To establish the method of quality standard for determining Naoxin’an Tablets.TLC was used as the identification method for Salvia miltiorrhiza Bunge,Kudzu-vine Root,Radix Polygoni Multiflori.The method of HPLC was developed to determine the ginsenoside R1,Rg1 and Rb1 in the Notoginseng.The TLC identification of minus was not disturbed the results.The Linear range of the ginsenoside R1,Rg1 and Rb1 were 0.18～1.66μg,0.606～5.454μg and 0.576～5.193μg,respectively.The average recovery were 99.37%,103.64%and 98.14%,respectively.The method was good at the specialty and repeatability,can provide the basis for the quality control of Naoxin’an Tablets. |
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| Keywords: | Naoxin’an tabLets QuaLity standard TLC HPLC |
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