电镜技术检验犬四联弱毒苗种子毒及品的外源病毒

我们用电子显微镜（电镜）技术，检验犬四联弱毒疫苗种子毒及其成品疫苗中的外源毒。经对每批种子毒细胞培养物及间隔一定批次成品疫苗抽样检查，其中一批种子毒细胞培养物中发现了呼肠病毒污染，得到及时有效的处理。同时证明应用电镜技术检验外源病毒确是一种快速而有效的方法。

Detection of Exotic Viruses in Canine Tetra Attenuated Vaccine Seed Virus andFinished Products by Electron Microscopy

Electron microscopy was used to detect exotic viruse comtamination in canine tetra attenuated vaccine seed virus or finished products.We sampled every batch of the seed virus cell cultures and specific batch of the vaccine at regular interval period, and the reovirus contamination was found in one batch of seed virus cell cultures, and was treated properly in time. The electron microscopic technique was proved as a rapid and efficient method to detect the exotic viruse contamination.