Antihyperglycemic effect of Cucurbita ficifolia fruit extract in streptozotocin-induced diabetic rats |
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Authors: | Xia Tao Wang Qin |
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Affiliation: | College of Life Science, East China Normal University, 3663 Zhongshang North Rd., Shanghai 200062, PR China. txia@bio.ecnu.edu.cn |
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Abstract: | In the present study, the antihyperglycemic effects of Cucurbita ficifolia fruit extract were investigated on streptozotocin-induced experimental diabetes in rats. Oral administration of the extract (300 and 600 mg/kg body weight, day) for 30 days resulted in a significant reduction in blood glucose, glycosylated haemoglobin, and an increase in plasma insulin and total haemoglobin. The effect was compared with 150 mg/kg b.w. tolbutamide. |
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Keywords: | Cucurbita ficifolia Hypoglycemic Streptozotocin |
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