Effect of anthelmintics on phosphatases in Ascaridia galli. |
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| Authors: | R Aggarwal S N Sanyal S Khera |
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| Affiliation: | Department of Zoology, Panjab University, Chandigarh, India. |
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| Abstract: | In vitro addition of the drugs tetramisole (TMS) and levamisole (LMS) caused an inhibition of the specific activities of acid phosphatase and Mg(++)-dependent adenosine triphosphatase. The inhibition was non-competitive in nature. No significant inhibition was caused by TMS in the activity of glucose-6-phosphatase, but LMS inhibited the enzyme in a non-competitive manner. The activity of alkaline phosphatase was, however, increased in the presence of both TMS and LMS. |
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