Polymorphism of the third component of canine complement |
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| Authors: | N.T. Gorman M.J. Hobart P.J. Lachmann |
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| Affiliation: | Mechanisms in Tumour Immunity Unit, Medical Research Council Centre, Hills Road, Cambridge CB2 2QH, England. |
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| Abstract: | In a series of 303 canine serum samples it has been found that there are three allotypes of canine C3, (F, FS and S) as detected by high voltage agar gel electrophoresis. Family studies showed that C3F and C3S are codominant genes at a single autosomal locus. The C3 locus was found to be linked neither to the major histocompatibility complex nor to the C6, C7 complex. |
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