Histone phosphorylation: stimulation by adenosine 3',5'-monophosphate |
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Authors: | T A Langan |
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Abstract: | Adenosine cyclic 3',5'-monophosphate at a concentration of 10-(7)M causes a four-to sixfold increase in the rate of histone phosphorylation catalyzed by a liver enzyme preparation. This observation suggests a mechanism for the induction of RNA synthesis by those hormones that cause increases in the concentration of cyclic AMP. |
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