| 家蚕、桑叶粗提物降血糖的作用效果 |
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| 引用本文： | 桂仲争,傅志强,刘金明,庄大桓,蔡幼民. 家蚕、桑叶粗提物降血糖的作用效果[J]. 蚕业科学, 2006, 32(1): 63-66 |
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| 作者姓名： | 桂仲争 傅志强 刘金明 庄大桓 蔡幼民 |
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| 作者单位： | 中国农业科学院蚕业研究所,镇江,212018;上海动物生物技术研究中心,中国农业科学院上海家畜寄生虫病研究所,上海,200232 |
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| 基金项目： | 江苏省高校高新技术产业发展项目 , 科技部专项基金 |
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| 摘 要： | 为进一步开发高效、多剂型的蚕、桑降血糖制剂,研究了不同品种的家蚕和桑叶粗提物降血糖的体外和体内实验效果。结果表明:家蚕提取物的降血糖效果明显优于桑叶粗提物;蚕品种间存在差异,桑品种间差异显著。灌胃家蚕和桑叶粗提物4周后的动物,其餐后血糖值分别降低了33.48%和24.24%。对不同蚕、桑品种降血糖差异的作用机理进行了探讨。
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| 关 键 词： | 家蚕 桑叶 粗提物 降血糖 |
| 文章编号： | 0257-4799（2006）01-0063-04 |
| 收稿时间： | 2005-08-22 |
| 修稿时间： | 2005-08-22 |
Effect of Extracts From Silkworm and Mulberry Leaves on Lowering Blood-glucose in Mice |
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| GUI Zhong-Zheng,FU Zhi-Qiang,LIU Jin-Ming,ZHUANG Da-Huan,CAI You-Min. Effect of Extracts From Silkworm and Mulberry Leaves on Lowering Blood-glucose in Mice[J]. Acta Sericologica Sinica, 2006, 32(1): 63-66 |
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| Authors: | GUI Zhong-Zheng FU Zhi-Qiang LIU Jin-Ming ZHUANG Da-Huan CAI You-Min |
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| Affiliation: | 1. The Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang Jiangsu 212018, China;2.Shanghai Center for Animal Biotechnique, Shanghai Institute of Animal Parasitology, Chinese Academy of Agricultural Sciences, Shanghai 200232, China |
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| Abstract: | In order to develop high effective and multiagents for lowering blood glucose of sericulture-related materials,we report here that extraction of the main component of lowering blood-glucose from silkworm and mulberry leaves,and its inhibitory effect on α-glucosidase in vitro and lowering blood-glucose in vivo.The results show that the extract from silkworm presents more effective to inhibit α-glucosidase in vitro than that from mulberry leaves.There exist the difference among silkworm varieties and significant difference among mulberry varieties.The blood glucose at postprandial in mice have been reduced by 33.48% and 24.24% after 4-week administration of the silkworm extract and mulberry leaves extract,respectively.The mechanism of difference among silkworm varieties and mulberry varieties to lowering blood-glucose has also been discussed. |
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| Keywords: | Bombyx mori Mulberry leaves Extract Lowering blood-glucose |
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