猪源隐孢子虫对仔猪致病性研究

为确定我国猪源隐孢子虫的危害性，采用光镜、扫描电镜和透射电镜等技术研究了猪源隐孢子虫sucp株对5日龄仔猪的致病性。结果：感染仔猪出现水样腹泻和脱水，粪便中混有肠黏膜碎片，潜伏期为3～5d，排卵囊持续期33-43d，虫体寄生于盲肠、结肠和直肠，并且盲肠和结肠杯状细胞增生，有炎性细胞浸润，结肠和直肠黏膜微绒毛萎缩、倒伏和脱落。结果表明sucp株对新生仔猪有一定致病性。

Pathogenicity of Cryptosporidium strain sucp in piglets

In order to study hazard of Cryptosporidium isolated from pigs in China, pathogenicity of Cryptosporidium strain sucp in 5-day-old piglets was investigated using pathological tissuesection technique, scaning electron microscope and transmission electron microscope technique. The results suggested that piglets inoculated excreted watery diarrhea and debris of mucous membrane, then dehydrated. Prepatent was 3-5 days, duration of oocyst excretion was 33-43 days. The development stages of the parasite were detected in cecum, colon and rectum of piglets, goblet cell proliferated and inflammation cells infiltrated in these sites. Microvilli in colon and rectum were in atrophy, lodging and shelling. It was concluded that 5-day-old piglets were moderately affected by Cryptosporidium strain sucp.