Serological investigation of Corynebacterium pseudotuberculosis infection in sheep--correlation between the hemolysis inhibition test and the ELISA test |
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| Authors: | J K Kuria G Holstad |
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| Institution: | 114.Department of Microbiology and Immunology, Norwegian College of Veterinary Medicine, P. O. Box 8146, Oslo Dep., N-0033 Oslo 1, Norway ;214.Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, University of Nairobi, Kenya |
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| Abstract: | Corynebacterium pseudotuberculosis causes caseous lymphadenitis in sheep and goats. The animals may be infected without showing clinical symptoms. Several serotests have therefore been employed to detect infected animals. Shen et al (1982) performed an enzyme linked immunosorbent assay (ELISA) to detect antibodies against the organism using cell wall antigens. Maki et al (1985) found that the toxin of the bacterium was a better antigen for assessing infection in the ELISA test. They reported that the antitoxin ELISA appeared to be as sensitive as the antihemolysin inhibition test (Zaki 1968). |
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