| 红芪多糖的体外抗氧化活性研究 |
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| 引用本文： | 惠和平,封士兰,胡芳弟,崔方,吴玉琼.红芪多糖的体外抗氧化活性研究[J].安徽农业科学,2010,38(8):4056-4057. |
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| 作者姓名： | 惠和平 封士兰 胡芳弟 崔方 吴玉琼 |
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| 作者单位： | 1. 兰州大学药学院,甘肃兰州,730000
2. 兰州大学药学院,甘肃兰州,730000;甘肃省新药临床前研究重点实验室,甘肃兰州,730000 |
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| 基金项目： | 甘肃省科技计划项目(0804WCGA134,0911WCCA005);;兰州市科技计划资助项目(07-1-33) |
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| 摘 要： | 目的]研究红芪多糖3（HPS-3）的抗氧化活性。方法]在体外化学模拟条件下,研究HPS-3对超氧阴离子（O2-.）、羟基自由基（.OH）、DPPH和过氧化氢（H2O2）的清除作用。结果]HPS-3具有一定的清除自由基的能力,在0.05～5.00mg/ml浓度范围内,对O2-.、H2O2、.OH及DPPH的最大清除率分别为55.92%、59.32%、53.69%和87.66%,且呈一定的量效依赖关系。结论]红芪多糖在体外有直接的抗氧化能力。
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| 关 键 词： | 红芪 多糖 抗氧化 |
Study on Antioxidative Activity of Polysaccharide from Radix Hedysari in vitro |
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| HUI He-ping et al.Study on Antioxidative Activity of Polysaccharide from Radix Hedysari in vitro[J].Journal of Anhui Agricultural Sciences,2010,38(8):4056-4057. |
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| Authors: | HUI He-ping |
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| Institution: | School of Pharmacy;Lanzhou University;Lanzhou;Gansu 730000 |
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| Abstract: | Objective]The research aimed to study the antioxidant activity of polysaccharide HPS-3 from Radix Hedysari Method]Under in vitro chemical simulated conditions,the scavenging effects of HPS-3's on superoxide anion(O_2~-·),hydroxyl radical (·OH),DPPH and H_2O_2 were measured for evaluating their antioxidant activity.Result]The results showed that HPS-3 had some functions of scavenging free radicals,in the concentration range of 0.05-5.00 mg/ml.The maximum scavenging rate on O_2~-·,H_2O_2,·OH and DPPH were 55.92%,59.32%,53.69%,87.66% respectively and there was a dose-dependent relationship.Conclusion]Polysaccharide from Radix Hedysari has distinctive antioxidant activity in vitro. |
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| Keywords: | Radix Hedysari Polysaccharide Antioxidant |
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