Botrytis cinerea — history of chemical control and novel fungicides for its management

Infections caused by Botrytis cinerea are of considerable economic importance in grapes, vegetables and berries world-wide, especially when grown under protection. Newly introduced botryticides are the anilinopyrimidines pyrimethanil, cyprodinil and mepanipyrim, the phenylpyrrol fludioxonil and the hydroxyanilide fenhexamid. Biochemical studies indicate that the anilinopyrimidines inhibit the biosynthesis of methionin by blocking cystathionine-β-lyase. The target site of fludioxonil seems to lie in the osmoregulatory signal transmission pathway. Although the exact biochemical target of fenhexamid is not yet characterized, there are clear indications that it is different from all other botryticides known. Therefore, fenhexamid is an effective tool for anti-resistance management strategies.