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胃肠黏膜屏障及应激对其的影响和干预措施
引用本文:马燕芬,胡红莲,高民,王丽芳.胃肠黏膜屏障及应激对其的影响和干预措施[J].动物营养学报,2012(9):1622-1627.
作者姓名:马燕芬  胡红莲  高民  王丽芳
作者单位:内蒙古农牧业科学院动物营养所
基金项目:现代农业产业技术体系建设专项;内蒙古农牧业科学院青年创新基金(2012QNJJM01;2011QNJJM03)
摘    要:应激可破坏胃肠道上皮细胞间紧密连接完整性,损伤胃肠黏膜屏障,并引发胃肠黏膜屏障障碍,增加其通透性,最终导致机体产生炎症反应,对其进行干预则可降低应激对胃肠通透性的影响。本文主要对胃肠黏膜屏障构成及其功能、胃肠黏膜屏障功能的评价和胃肠通透性的测定、应激对胃肠黏膜屏障的影响及干预措施进行了综述,以期为缓解应激对胃肠黏膜屏障功能的影响提供参考。

关 键 词:应激  胃肠黏膜屏障  干预

Gastrointestinal Mucosal Barrier:Effects of Stress and Intervention
MA Yanfen,HU Honglian,GAO Min,WANG Lifang.Gastrointestinal Mucosal Barrier:Effects of Stress and Intervention[J].Acta Zoonutrimenta Sinica,2012(9):1622-1627.
Authors:MA Yanfen  HU Honglian  GAO Min  WANG Lifang
Institution:(Animal Nutrition Institute,Agriculture and Animal Husbandry Academy of Inner Mongolia,Huhhot 010031,China)
Abstract:Stress can damage tight junction integrity and gastrointestinal mucosal barrier,cause gastrointestinal mucosal barrier dysfunction,and increase the gastrointestinal tract permeability,which ultimately cause the body to produce the inflammatory response.Its intervention can reduce the impact of stress on gastrointestinal permeability.The compositions and functions of gastrointestinal barrier,assessing of gastrointestinal barrier function and measuring of gastrointestinal permeability,and effects of stress on gastrointestinal mucosal barrier and intervention were reviewed in this paper,in order to provide reference for relieving the effects of stress on gastrointestinal mucosal barrier function.
Keywords:stress  gastrointestinal mucosal barrier  intervention
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